TY  - GEN
AU  - McNeill,Robert S
AU  - Canoutas,Demitra A
AU  - Stuhlmiller,Timothy J
AU  - Dhruv,Harshil D
AU  - Irvin,David M
AU  - Bash,Ryan E
AU  - Angus,Steven P
AU  - Herring,Laura E
AU  - Simon,Jeremy M
AU  - Skinner,Kasey R
AU  - Limas,Juanita C
AU  - Chen,Xin
AU  - Schmid,Ralf S
AU  - Siegel,Marni B
AU  - Van Swearingen,Amanda E D
AU  - Hadler,Michael J
AU  - Sulman,Erik P
AU  - Sarkaria,Jann N
AU  - Anders,Carey K
AU  - Graves,Lee M
AU  - Berens,Michael E
AU  - Johnson,Gary L
AU  - Miller,C Ryan
TI  - Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma
SN  - 1523-5866
PY  - 2018///0627
KW  - Animals
KW  - Apoptosis
KW  - drug effects
KW  - Brain Neoplasms
KW  - drug therapy
KW  - Cell Proliferation
KW  - Drug Resistance, Neoplasm
KW  - Drug Synergism
KW  - Glioblastoma
KW  - Humans
KW  - Mice
KW  - Mitogen-Activated Protein Kinases
KW  - antagonists & inhibitors
KW  - Phosphoinositide-3 Kinase Inhibitors
KW  - Phosphorylation
KW  - Protein Kinase Inhibitors
KW  - pharmacology
KW  - Signal Transduction
KW  - Tumor Cells, Cultured
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1093/neuonc/nox044
ER  -