McNeill, Robert S <br/><br/>
Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma.  [electronic resource] 

 -  Neuro-oncology  Oct 2017 
 - 1469-1480 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1523-5866 
<br/><br/><label>Standard No.: </label>10.1093/neuonc/nox044  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Apoptosis--drug effects<br/>Brain Neoplasms--drug therapy<br/>Cell Proliferation--drug effects<br/>Drug Resistance, Neoplasm<br/>Drug Synergism<br/>Glioblastoma--drug therapy<br/>Humans<br/>Mice<br/>Mitogen-Activated Protein Kinases--antagonists & inhibitors<br/>Phosphoinositide-3 Kinase Inhibitors<br/>Phosphorylation<br/>Protein Kinase Inhibitors--pharmacology<br/>Signal Transduction--drug effects<br/>Tumor Cells, Cultured<br/>Xenograft Model Antitumor Assays