TY  - GEN
AU  - Cassa,Christopher A
AU  - Weghorn,Donate
AU  - Balick,Daniel J
AU  - Jordan,Daniel M
AU  - Nusinow,David
AU  - Samocha,Kaitlin E
AU  - O'Donnell-Luria,Anne
AU  - MacArthur,Daniel G
AU  - Daly,Mark J
AU  - Beier,David R
AU  - Sunyaev,Shamil R
TI  - Estimating the selective effects of heterozygous protein-truncating variants from human exome data
SN  - 1546-1718
PY  - 2017///0918
KW  - Algorithms
KW  - Animals
KW  - Bayes Theorem
KW  - Exome
KW  - genetics
KW  - Gene Frequency
KW  - Genetic Predisposition to Disease
KW  - Genetic Variation
KW  - Genome-Wide Association Study
KW  - methods
KW  - Genotype
KW  - Heterozygote
KW  - Humans
KW  - Mice, Knockout
KW  - Models, Genetic
KW  - Mutation
KW  - Selection, Genetic
KW  - Sequence Analysis, DNA
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1038/ng.3831
ER  -