TY - GEN AU - Huang,Yi-Jie AU - Chang,Chi-Sen AU - Peng,Yen-Chun AU - Yeh,Hong-Zen AU - Yang,Sheng-Shun TI - On-treatment HBV DNA dynamics predict virological breakthrough in entecavir-treated HBeAg-positive chronic hepatitis B SN - 1932-6203 PY - 2017///0828 KW - Adult KW - Antiviral Agents KW - therapeutic use KW - DNA, Viral KW - genetics KW - Drug Resistance, Viral KW - Female KW - Guanine KW - analogs & derivatives KW - Hepatitis B e Antigens KW - metabolism KW - Hepatitis B virus KW - drug effects KW - Hepatitis B, Chronic KW - drug therapy KW - Humans KW - Male KW - Middle Aged KW - Multivariate Analysis KW - Prognosis KW - Retrospective Studies KW - Time Factors KW - Treatment Outcome KW - Viral Load N1 - Publication Type: Journal Article UR - https://doi.org/10.1371/journal.pone.0174046 ER -