Alizadeh, Javad <br/><br/>
Mevalonate Cascade Inhibition by Simvastatin Induces the Intrinsic Apoptosis Pathway via Depletion of Isoprenoids in Tumor Cells.  [electronic resource] 

 -  Scientific reports  03 2017 
 - 44841 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>2045-2322 
<br/><br/><label>Standard No.: </label>10.1038/srep44841  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Alkyl and Aryl Transferases--metabolism<br/>Apoptosis--drug effects<br/>Cell Death--drug effects<br/>Cell Line, Tumor<br/>Cell Membrane--metabolism<br/>Cholesterol--metabolism<br/>Dose-Response Relationship, Drug<br/>Farnesyltranstransferase--metabolism<br/>Humans<br/>Hydroxymethylglutaryl-CoA Reductase Inhibitors--pharmacology<br/>Metabolic Networks and Pathways--drug effects<br/>Mevalonic Acid--metabolism<br/>Protein Transport<br/>Signal Transduction--drug effects<br/>Simvastatin--pharmacology<br/>Terpenes<br/>rho GTP-Binding Proteins--metabolism