TY - GEN AU - Zhu,Xiandi AU - Sun,Yn AU - Chen,Di AU - Li,Jingfeng AU - Dong,Xia AU - Wang,Jie AU - Chen,Huaiwen AU - Wang,Ying AU - Zhang,Fulei AU - Dai,Jinaxin AU - Pirraco,Rogério P AU - Guo,Shangjing AU - Marques,Alexandra P AU - Reis,Rui L AU - Li,Wei TI - Mastocarcinoma therapy synergistically promoted by lysosome dependent apoptosis specifically evoked by 5-Fu@nanogel system with passive targeting and pH activatable dual function SN - 1873-4995 PY - 2018///1002 KW - Animals KW - Antineoplastic Agents KW - administration & dosage KW - Apoptosis KW - drug effects KW - Breast Neoplasms KW - drug therapy KW - Caspase 9 KW - metabolism KW - Cathepsin B KW - Cell Line, Tumor KW - Cell Membrane Permeability KW - Cytochromes c KW - Drug Carriers KW - Female KW - Fluorouracil KW - Gels KW - Humans KW - Hydrogen-Ion Concentration KW - Imines KW - chemistry KW - Lysosomes KW - Membrane Potential, Mitochondrial KW - Mice, Inbred BALB C KW - Mice, Nude KW - Mitochondria KW - Molecular Targeted Therapy KW - Nanostructures KW - Particle Size KW - Polyethylenes N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.jconrel.2017.03.038 ER -