Koole, Cassandra

Genetically encoded photocross-linkers determine the biological binding site of exendin-4 peptide in the N-terminal domain of the intact human glucagon-like peptide-1 receptor (GLP-1R). [electronic resource] - The Journal of biological chemistry 04 2017 - 7131-7144 p. digital

Publication Type: Journal Article

1083-351X

10.1074/jbc.M117.779496 doi


Azides--chemistry
Binding Sites
Cyclic AMP--metabolism
Diabetes Mellitus, Type 2--metabolism
Exenatide
Glucagon-Like Peptide-1 Receptor--chemistry
HEK293 Cells
Humans
Ligands
Molecular Dynamics Simulation
Molecular Structure
Mutagenesis
Mutation
Peptides--chemistry
Phenylalanine--analogs & derivatives
Protein Domains
Protein Multimerization
Structure-Activity Relationship
Ultraviolet Rays
Venoms--chemistry