TY - GEN AU - Pan,Chun-Wu AU - Jin,Xin AU - Zhao,Yu AU - Pan,Yunqian AU - Yang,Jing AU - Karnes,R Jeffrey AU - Zhang,Jun AU - Wang,Liguo AU - Huang,Haojie TI - AKT-phosphorylated FOXO1 suppresses ERK activation and chemoresistance by disrupting IQGAP1-MAPK interaction SN - 1460-2075 PY - 2017///0428 KW - Animals KW - Bridged-Ring Compounds KW - pharmacology KW - Cell Line, Tumor KW - Drug Resistance, Neoplasm KW - Forkhead Box Protein O1 KW - genetics KW - Humans KW - MAP Kinase Signaling System KW - Male KW - Mice KW - Mice, Inbred NOD KW - Mice, SCID KW - Mitogen-Activated Protein Kinase 1 KW - Mitogen-Activated Protein Kinase 3 KW - Phosphatidylinositol 3-Kinases KW - Phosphoinositide-3 Kinase Inhibitors KW - Phosphorylation KW - Prostatic Neoplasms KW - Proto-Oncogene Proteins c-akt KW - Taxoids KW - Xenograft Model Antitumor Assays KW - ras GTPase-Activating Proteins N1 - Publication Type: Journal Article UR - https://doi.org/10.15252/embj.201695534 ER -