TY - GEN AU - Hu,Shi AU - Fu,Wenyan AU - Li,Tian AU - Yuan,Qingning AU - Wang,Feifei AU - Lv,Gaojian AU - Lv,Yuanyuan AU - Fan,Xiaoyan AU - Shen,Yafeng AU - Lin,Fangxing AU - Tang,Ying AU - Ye,Xuting AU - Yang,Yongji AU - Lei,Changhai TI - Antagonism of EGFR and Notch limits resistance to EGFR inhibitors and radiation by decreasing tumor-initiating cell frequency SN - 1946-6242 PY - 2017///1218 KW - Aldehyde Dehydrogenase KW - metabolism KW - Animals KW - Antibodies KW - pharmacology KW - Antineoplastic Agents KW - Carcinogenesis KW - pathology KW - Carcinoma, Non-Small-Cell Lung KW - drug therapy KW - Cell Count KW - Cell Line, Tumor KW - Cell Proliferation KW - drug effects KW - Drug Resistance, Neoplasm KW - Epithelial-Mesenchymal Transition KW - ErbB Receptors KW - antagonists & inhibitors KW - Lung Neoplasms KW - Mice, SCID KW - Molecular Targeted Therapy KW - Neoplasm Recurrence, Local KW - Neoplastic Stem Cells KW - Protein Kinase Inhibitors KW - Radiation Tolerance KW - Receptors, Notch KW - Signal Transduction N1 - Publication Type: Journal Article UR - https://doi.org/10.1126/scitranslmed.aag0339 ER -