Kazi, Julhash U <br/><br/>
Tyrosine 842 in the activation loop is required for full transformation by the oncogenic mutant FLT3-ITD.  [electronic resource] 

 -  Cellular and molecular life sciences : CMLS  07 2017 
 - 2679-2688 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1420-9071 
<br/><br/><label>Standard No.: </label>10.1007/s00018-017-2494-0  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Apoptosis<br/>Cell Line<br/>Cell Proliferation<br/>Cell Transformation, Neoplastic--metabolism<br/>Down-Regulation<br/>Enzyme Activation<br/>Extracellular Signal-Regulated MAP Kinases--metabolism<br/>Gene Duplication<br/>Humans<br/>Male<br/>Mice, Inbred BALB C<br/>Mutant Proteins--metabolism<br/>Mutation--genetics<br/>Myeloid Cells--metabolism<br/>Oncogenes<br/>Phosphorylation<br/>Protein Stability<br/>Protein Tyrosine Phosphatase, Non-Receptor Type 11--metabolism<br/>Proteolysis<br/>Signal Transduction<br/>Tyrosine--metabolism<br/>Ubiquitination<br/>fms-Like Tyrosine Kinase 3--chemistry