TY  - GEN
AU  - Gopalsamy,Ariamala
AU  - Narayanan,Arjun
AU  - Liu,Shenping
AU  - Parikh,Mihir D
AU  - Kyne,Robert E
AU  - Fadeyi,Olugbeminiyi
AU  - Tones,Michael A
AU  - Cherry,Jonathan J
AU  - Nabhan,Joseph F
AU  - LaRosa,Gregory
AU  - Petersen,Donna N
AU  - Menard,Carol
AU  - Foley,Timothy L
AU  - Noell,Stephen
AU  - Ren,Yong
AU  - Loria,Paula M
AU  - Maglich-Goodwin,Jodi
AU  - Rong,Haojing
AU  - Jones,Lyn H
TI  - Design of Potent mRNA Decapping Scavenger Enzyme (DcpS) Inhibitors with Improved Physicochemical Properties To Investigate the Mechanism of Therapeutic Benefit in Spinal Muscular Atrophy (SMA)
SN  - 1520-4804
PY  - 2017///0424
KW  - Animals
KW  - Disease Models, Animal
KW  - Drug Design
KW  - Endoribonucleases
KW  - antagonists & inhibitors
KW  - Enzyme Inhibitors
KW  - chemistry
KW  - HEK293 Cells
KW  - Humans
KW  - Mice
KW  - Molecular Docking Simulation
KW  - Muscular Atrophy, Spinal
KW  - drug therapy
KW  - Quinazolines
KW  - RNA, Messenger
KW  - Survival of Motor Neuron 2 Protein
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/acs.jmedchem.7b00124
ER  -