Salvianolic acid B inhibits IL-1β-induced inflammatory cytokine production in human osteoarthritis chondrocytes and has a protective effect in a mouse osteoarthritis model. [electronic resource]
- International immunopharmacology May 2017
- 31-37 p. digital
Publication Type: Journal Article
1878-1705
10.1016/j.intimp.2017.02.021 doi
Animals Anti-Inflammatory Agents--therapeutic use Benzofurans--therapeutic use Cartilage--pathology Chondrocytes--drug effects Cytokines--metabolism Disease Models, Animal Humans Inflammation--drug therapy Interleukin-1beta--immunology Male Matrix Metalloproteinase 13 Menisci, Tibial--surgery Mice Mice, Inbred C57BL NF-kappa B--metabolism Nitric Oxide--metabolism Osteoarthritis--drug therapy Phosphorylation--drug effects Signal Transduction--drug effects