TY - GEN AU - Rajamani,Karthyayani AU - Liu,Jen-Wei AU - Wu,Cheng-Han AU - Chiang,I-Tsang AU - You,Deng-Huwei AU - Lin,Si-Yin AU - Hsieh,Dean-Kuo AU - Lin,Shinn-Zong AU - Harn,Horng-Jyh AU - Chiou,Tzyy-Wen TI - n-Butylidenephthalide exhibits protection against neurotoxicity through regulation of tryptophan 2, 3 dioxygenase in spinocerebellar ataxia type 3 SN - 1873-7064 PY - 2018///0503 KW - Animals KW - Ataxin-3 KW - metabolism KW - Calcium KW - Calpain KW - Cerebellum KW - drug effects KW - Disease Models, Animal KW - HEK293 Cells KW - Humans KW - Machado-Joseph Disease KW - drug therapy KW - Mice, Inbred C57BL KW - Mice, Transgenic KW - Motor Activity KW - Neuroprotective Agents KW - pharmacology KW - Phthalic Anhydrides KW - Quinolinic Acid KW - administration & dosage KW - Ryanodine Receptor Calcium Release Channel KW - Tryptophan KW - Tryptophan Oxygenase N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.neuropharm.2017.02.014 ER -