Rajamani, Karthyayani

n-Butylidenephthalide exhibits protection against neurotoxicity through regulation of tryptophan 2, 3 dioxygenase in spinocerebellar ataxia type 3. [electronic resource] - Neuropharmacology 05 2017 - 434-446 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1873-7064

10.1016/j.neuropharm.2017.02.014 doi


Animals
Ataxin-3--metabolism
Calcium--metabolism
Calpain--metabolism
Cerebellum--drug effects
Disease Models, Animal
HEK293 Cells
Humans
Machado-Joseph Disease--drug therapy
Mice, Inbred C57BL
Mice, Transgenic
Motor Activity--drug effects
Neuroprotective Agents--pharmacology
Phthalic Anhydrides--pharmacology
Quinolinic Acid--administration & dosage
Ryanodine Receptor Calcium Release Channel--metabolism
Tryptophan--metabolism
Tryptophan Oxygenase--metabolism