TY - GEN AU - Wang,Hong AU - Guo,Haoran AU - Su,Jiaming AU - Rui,Yajuan AU - Zheng,Wenwen AU - Gao,Wenying AU - Zhang,Wenyan AU - Li,Zhaolong AU - Liu,Guanchen AU - Markham,Richard B AU - Wei,Wei AU - Yu,Xiao-Fang TI - Inhibition of Vpx-Mediated SAMHD1 and Vpr-Mediated Host Helicase Transcription Factor Degradation by Selective Disruption of Viral CRL4 (DCAF1) E3 Ubiquitin Ligase Assembly SN - 1098-5514 PY - 2017///0515 KW - Carrier Proteins KW - metabolism KW - Cell Line KW - DNA-Binding Proteins KW - Ethylenediamines KW - pharmacology KW - G2 Phase Cell Cycle Checkpoints KW - HEK293 Cells KW - HIV Infections KW - virology KW - HIV-1 KW - Host-Pathogen Interactions KW - Humans KW - Monomeric GTP-Binding Proteins KW - Myeloid Cells KW - Protein Serine-Threonine Kinases KW - Protein Structure, Tertiary KW - SAM Domain and HD Domain-Containing Protein 1 KW - Simian Immunodeficiency Virus KW - Transcription Factors KW - Ubiquitin-Protein Ligases KW - Viral Regulatory and Accessory Proteins KW - genetics KW - Virus Replication KW - Zinc KW - vpr Gene Products, Human Immunodeficiency Virus N1 - Publication Type: Journal Article UR - https://doi.org/10.1128/JVI.00225-17 ER -