TY  - GEN
AU  - Jiang,Wenchun
AU  - Li,Xin
AU  - Li,Tongyu
AU  - Wang,Hailian
AU  - Shi,Wei
AU  - Qi,Ping
AU  - Li,Chunyang
AU  - Chen,Jie
AU  - Bao,Jinku
AU  - Huang,Guodong
AU  - Wang,Yi
TI  - Repositioning of amprenavir as a novel extracellular signal-regulated kinase-2 inhibitor and apoptosis inducer in MCF-7 human breast cancer
SN  - 1791-2423
PY  - 2017///0613
KW  - Animals
KW  - Antineoplastic Agents
KW  - therapeutic use
KW  - Apoptosis
KW  - drug effects
KW  - Bcl-2-Like Protein 11
KW  - genetics
KW  - Breast Neoplasms
KW  - drug therapy
KW  - Carbamates
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Cell Survival
KW  - Drug Repositioning
KW  - methods
KW  - Female
KW  - Furans
KW  - HIV Protease Inhibitors
KW  - Humans
KW  - MCF-7 Cells
KW  - Male
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mice, Nude
KW  - Mitogen-Activated Protein Kinase 1
KW  - antagonists & inhibitors
KW  - Molecular Docking Simulation
KW  - Molecular Dynamics Simulation
KW  - Phosphorylation
KW  - RNA Interference
KW  - RNA, Small Interfering
KW  - Signal Transduction
KW  - Sulfonamides
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.3892/ijo.2017.3860
ER  -