Jiang, Wenchun <br/><br/>
Repositioning of amprenavir as a novel extracellular signal-regulated kinase-2 inhibitor and apoptosis inducer in MCF-7 human breast cancer.  [electronic resource] 

 -  International journal of oncology  Mar 2017 
 - 823-834 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1791-2423 
<br/><br/><label>Standard No.: </label>10.3892/ijo.2017.3860  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--therapeutic use<br/>Apoptosis--drug effects<br/>Bcl-2-Like Protein 11--genetics<br/>Breast Neoplasms--drug therapy<br/>Carbamates--therapeutic use<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Cell Survival--drug effects<br/>Drug Repositioning--methods<br/>Female<br/>Furans<br/>HIV Protease Inhibitors--therapeutic use<br/>Humans<br/>MCF-7 Cells<br/>Male<br/>Mice<br/>Mice, Inbred C57BL<br/>Mice, Nude<br/>Mitogen-Activated Protein Kinase 1--antagonists & inhibitors<br/>Molecular Docking Simulation<br/>Molecular Dynamics Simulation<br/>Phosphorylation--drug effects<br/>RNA Interference<br/>RNA, Small Interfering--genetics<br/>Signal Transduction--drug effects<br/>Sulfonamides--therapeutic use<br/>Xenograft Model Antitumor Assays