TY  - GEN
AU  - Dilly,Suzanne J
AU  - Clark,Andrew J
AU  - Marsh,Andrew
AU  - Mitchell,Daniel A
AU  - Cain,Ricky
AU  - Fishwick,Colin W G
AU  - Taylor,Paul C
TI  - A chemical genomics approach to drug reprofiling in oncology: Antipsychotic drug risperidone as a potential adenocarcinoma treatment
SN  - 1872-7980
PY  - 2017///0814
KW  - 17-Hydroxysteroid Dehydrogenases
KW  - antagonists & inhibitors
KW  - 3-Hydroxyacyl CoA Dehydrogenases
KW  - Adenocarcinoma
KW  - drug therapy
KW  - Animals
KW  - Antineoplastic Agents
KW  - chemistry
KW  - Antipsychotic Agents
KW  - Bacteriophage T7
KW  - genetics
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - drug effects
KW  - Dose-Response Relationship, Drug
KW  - Drosophila melanogaster
KW  - Drug Compounding
KW  - Drug Repositioning
KW  - methods
KW  - Enzyme Inhibitors
KW  - Gene Library
KW  - Genomics
KW  - Humans
KW  - Linoleic Acids, Conjugated
KW  - Male
KW  - Mice, Nude
KW  - Molecular Docking Simulation
KW  - Molecular Targeted Therapy
KW  - Prostatic Neoplasms
KW  - Protein Conformation
KW  - Risperidone
KW  - Structure-Activity Relationship
KW  - Time Factors
KW  - Tumor Burden
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.canlet.2017.01.042
ER  -