TY - GEN AU - Kozuka,Chisayo AU - Shimizu-Okabe,Chigusa AU - Takayama,Chitoshi AU - Nakano,Kaku AU - Morinaga,Hidetaka AU - Kinjo,Ayano AU - Fukuda,Kotaro AU - Kamei,Asuka AU - Yasuoka,Akihito AU - Kondo,Takashi AU - Abe,Keiko AU - Egashira,Kensuke AU - Masuzaki,Hiroaki TI - Marked augmentation of PLGA nanoparticle-induced metabolically beneficial impact of γ-oryzanol on fuel dyshomeostasis in genetically obese-diabetic ob/ob mice SN - 1521-0464 PY - 2017///0403 KW - Administration, Oral KW - Animals KW - Behavior, Animal KW - drug effects KW - Blood Glucose KW - Diabetes Mellitus KW - blood KW - Disease Models, Animal KW - Dose-Response Relationship, Drug KW - Drug Administration Schedule KW - Drug Carriers KW - Drug Compounding KW - Endoplasmic Reticulum Stress KW - Energy Metabolism KW - Food Preferences KW - Gastrointestinal Microbiome KW - Hypoglycemic Agents KW - administration & dosage KW - Hypolipidemic Agents KW - Insulin Resistance KW - Intestinal Absorption KW - Islets of Langerhans KW - Lactic Acid KW - Lipids KW - Liver KW - Male KW - Mice, Obese KW - Nanomedicine KW - Nanoparticles KW - Obesity KW - Phenylpropionates KW - Polyglycolic Acid KW - Polylactic Acid-Polyglycolic Acid Copolymer KW - Solubility KW - Technology, Pharmaceutical KW - methods KW - Time Factors N1 - Publication Type: Journal Article UR - https://doi.org/10.1080/10717544.2017.1279237 ER -