TY  - GEN
AU  - Swords,R T
AU  - Watts,J
AU  - Erba,H P
AU  - Altman,J K
AU  - Maris,M
AU  - Anwer,F
AU  - Hua,Z
AU  - Stein,H
AU  - Faessel,H
AU  - Sedarati,F
AU  - Dezube,B J
AU  - Giles,F J
AU  - Medeiros,B C
AU  - DeAngelo,D J
TI  - Expanded safety analysis of pevonedistat, a first-in-class NEDD8-activating enzyme inhibitor, in patients with acute myeloid leukemia and myelodysplastic syndromes
SN  - 2044-5385
PY  - 2018///0827
KW  - Adult
KW  - Aged
KW  - Aged, 80 and over
KW  - Cyclopentanes
KW  - administration & dosage
KW  - Enzyme Inhibitors
KW  - Female
KW  - Humans
KW  - Leukemia, Myeloid, Acute
KW  - drug therapy
KW  - Male
KW  - Maximum Tolerated Dose
KW  - Middle Aged
KW  - Myelodysplastic Syndromes
KW  - NEDD8 Protein
KW  - antagonists & inhibitors
KW  - Pyrimidines
KW  - Young Adult
N1  - Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/bcj.2017.1
ER  -