TY  - GEN
AU  - McColm,Juliet
AU  - Brittain,Claire
AU  - Suriyapperuma,Subha
AU  - Swanson,Steven
AU  - Tauscher-Wisniewski,Sitra
AU  - Foster,Joanne
AU  - Soon,Danny
AU  - Jackson,Kimberley
TI  - Evaluation of single and multiple doses of a novel mGlu2 agonist, a potential antipsychotic therapy, in healthy subjects
SN  - 1365-2125
PY  - 2018///0412
KW  - Administration, Oral
KW  - Adult
KW  - Aged
KW  - Area Under Curve
KW  - Bridged Bicyclo Compounds
KW  - blood
KW  - Cohort Studies
KW  - Disorders of Excessive Somnolence
KW  - chemically induced
KW  - Dizziness
KW  - Dose-Response Relationship, Drug
KW  - Double-Blind Method
KW  - Half-Life
KW  - Headache
KW  - Healthy Volunteers
KW  - Humans
KW  - Male
KW  - Middle Aged
KW  - Nausea
KW  - Placebos
KW  - Prodrugs
KW  - pharmacology
KW  - Receptors, Metabotropic Glutamate
KW  - agonists
KW  - Triazoles
KW  - Vomiting
KW  - Young Adult
N1  - Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1111/bcp.13252
ER  -