McColm, Juliet

Evaluation of single and multiple doses of a novel mGlu2 agonist, a potential antipsychotic therapy, in healthy subjects. [electronic resource] - British journal of clinical pharmacology 08 2017 - 1654-1667 p. digital

Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

1365-2125

10.1111/bcp.13252 doi


Administration, Oral
Adult
Aged
Area Under Curve
Bridged Bicyclo Compounds--blood
Cohort Studies
Disorders of Excessive Somnolence--chemically induced
Dizziness--chemically induced
Dose-Response Relationship, Drug
Double-Blind Method
Half-Life
Headache
Healthy Volunteers
Humans
Male
Middle Aged
Nausea--chemically induced
Placebos
Prodrugs--pharmacology
Receptors, Metabotropic Glutamate--agonists
Triazoles--blood
Vomiting--chemically induced
Young Adult