McColm, Juliet Evaluation of single and multiple doses of a novel mGlu2 agonist, a potential antipsychotic therapy, in healthy subjects. [electronic resource] - British journal of clinical pharmacology 08 2017 - 1654-1667 p. digital Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't ISSN: 1365-2125 Standard No.: 10.1111/bcp.13252 doi Subjects--Topical Terms: Administration, OralAdultAgedArea Under CurveBridged Bicyclo Compounds--bloodCohort StudiesDisorders of Excessive Somnolence--chemically inducedDizziness--chemically inducedDose-Response Relationship, DrugDouble-Blind MethodHalf-LifeHeadacheHealthy VolunteersHumansMaleMiddle AgedNausea--chemically inducedPlacebosProdrugs--pharmacologyReceptors, Metabotropic Glutamate--agonistsTriazoles--bloodVomiting--chemically inducedYoung Adult