TY  - GEN
AU  - Wu,Darrell
AU  - Ren,Pingping
AU  - Zheng,Yanqiu
AU  - Zhang,Lin
AU  - Xu,Gaiping
AU  - Xie,Wanmu
AU  - Lloyd,Eric E
AU  - Zhang,Sui
AU  - Zhang,Qianzi
AU  - Curci,John A
AU  - Coselli,Joseph S
AU  - Milewicz,Dianna M
AU  - Shen,Ying H
AU  - LeMaire,Scott A
TI  - NLRP3 (Nucleotide Oligomerization Domain-Like Receptor Family, Pyrin Domain Containing 3)-Caspase-1 Inflammasome Degrades Contractile Proteins: Implications for Aortic Biomechanical Dysfunction and Aneurysm and Dissection Formation
SN  - 1524-4636
PY  - 2017///0621
KW  - Aged
KW  - Aortic Dissection
KW  - enzymology
KW  - Angiotensin II
KW  - Animals
KW  - Aorta, Abdominal
KW  - drug effects
KW  - Aorta, Thoracic
KW  - Aortic Aneurysm, Abdominal
KW  - Aortic Aneurysm, Thoracic
KW  - Biomechanical Phenomena
KW  - Caspase 1
KW  - deficiency
KW  - Cells, Cultured
KW  - Disease Models, Animal
KW  - Female
KW  - Genetic Predisposition to Disease
KW  - Glyburide
KW  - pharmacology
KW  - Humans
KW  - Inflammasomes
KW  - antagonists & inhibitors
KW  - Male
KW  - Mice, 129 Strain
KW  - Mice, Inbred C57BL
KW  - Mice, Knockout
KW  - Middle Aged
KW  - Muscle Proteins
KW  - metabolism
KW  - Muscle, Smooth, Vascular
KW  - Myocytes, Smooth Muscle
KW  - NLR Family, Pyrin Domain-Containing 3 Protein
KW  - Phenotype
KW  - Proteolysis
KW  - Vasoconstriction
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1161/ATVBAHA.116.307648
ER  -