Wu, Darrell <br/><br/>
NLRP3 (Nucleotide Oligomerization Domain-Like Receptor Family, Pyrin Domain Containing 3)-Caspase-1 Inflammasome Degrades Contractile Proteins: Implications for Aortic Biomechanical Dysfunction and Aneurysm and Dissection Formation.  [electronic resource] 

 -  Arteriosclerosis, thrombosis, and vascular biology  04 2017 
 - 694-706 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1524-4636 
<br/><br/><label>Standard No.: </label>10.1161/ATVBAHA.116.307648  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Aged<br/>Aortic Dissection--enzymology<br/>Angiotensin II<br/>Animals<br/>Aorta, Abdominal--drug effects<br/>Aorta, Thoracic--drug effects<br/>Aortic Aneurysm, Abdominal--enzymology<br/>Aortic Aneurysm, Thoracic--enzymology<br/>Biomechanical Phenomena<br/>Caspase 1--deficiency<br/>Cells, Cultured<br/>Disease Models, Animal<br/>Female<br/>Genetic Predisposition to Disease<br/>Glyburide--pharmacology<br/>Humans<br/>Inflammasomes--antagonists & inhibitors<br/>Male<br/>Mice, 129 Strain<br/>Mice, Inbred C57BL<br/>Mice, Knockout<br/>Middle Aged<br/>Muscle Proteins--metabolism<br/>Muscle, Smooth, Vascular--drug effects<br/>Myocytes, Smooth Muscle--drug effects<br/>NLR Family, Pyrin Domain-Containing 3 Protein--deficiency<br/>Phenotype<br/>Proteolysis<br/>Vasoconstriction--drug effects