TY  - GEN
AU  - Andrade-Pavón,Dulce
AU  - Cuevas-Hernández,Roberto I
AU  - Trujillo-Ferrara,José G
AU  - Hernández-Rodríguez,César
AU  - Ibarra,J Antonio
AU  - Villa-Tanaca,Lourdes
TI  - Recombinant 3-Hydroxy 3-Methyl Glutaryl-CoA Reductase from Candida glabrata (Rec-CgHMGR) Obtained by Heterologous Expression, as a Novel Therapeutic Target Model for Testing Synthetic Drugs
SN  - 1559-0291
PY  - 2017///0908
KW  - Amino Acid Sequence
KW  - Biocatalysis
KW  - Candida glabrata
KW  - enzymology
KW  - Drug Evaluation, Preclinical
KW  - Enzyme Stability
KW  - Escherichia coli
KW  - genetics
KW  - Humans
KW  - Hydrogen-Ion Concentration
KW  - Hydroxymethylglutaryl CoA Reductases
KW  - chemistry
KW  - Hydroxymethylglutaryl-CoA Reductase Inhibitors
KW  - chemical synthesis
KW  - Kinetics
KW  - Maltose-Binding Proteins
KW  - metabolism
KW  - Models, Molecular
KW  - Molecular Targeted Therapy
KW  - Protein Domains
KW  - Recombinant Proteins
KW  - Simvastatin
KW  - pharmacology
KW  - Solubility
KW  - Substrate Specificity
KW  - Temperature
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1007/s12010-017-2412-9
ER  -