Andrade-Pavón, Dulce <br/><br/>
Recombinant 3-Hydroxy 3-Methyl Glutaryl-CoA Reductase from Candida glabrata (Rec-CgHMGR) Obtained by Heterologous Expression, as a Novel Therapeutic Target Model for Testing Synthetic Drugs.  [electronic resource] 

 -  Applied biochemistry and biotechnology  Aug 2017 
 - 1478-1490 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1559-0291 
<br/><br/><label>Standard No.: </label>10.1007/s12010-017-2412-9  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amino Acid Sequence<br/>Biocatalysis<br/>Candida glabrata--enzymology<br/>Drug Evaluation, Preclinical<br/>Enzyme Stability<br/>Escherichia coli--genetics<br/>Humans<br/>Hydrogen-Ion Concentration<br/>Hydroxymethylglutaryl CoA Reductases--chemistry<br/>Hydroxymethylglutaryl-CoA Reductase Inhibitors--chemical synthesis<br/>Kinetics<br/>Maltose-Binding Proteins--metabolism<br/>Models, Molecular<br/>Molecular Targeted Therapy<br/>Protein Domains<br/>Recombinant Proteins--chemistry<br/>Simvastatin--pharmacology<br/>Solubility<br/>Substrate Specificity<br/>Temperature