TY - GEN AU - Xi,Guifa AU - Li,Yuping Derek AU - Grahovac,Gordan AU - Rajaram,Veena AU - Wadhwani,Nitin AU - Pundy,Tatiana AU - Mania-Farnell,Barbara AU - James,Charles David AU - Tomita,Tadanori TI - Targeting CD133 improves chemotherapeutic efficacy of recurrent pediatric pilocytic astrocytoma following prolonged chemotherapy SN - 1476-4598 PY - 2018///0205 KW - AC133 Antigen KW - antagonists & inhibitors KW - ATP Binding Cassette Transporter, Subfamily B KW - metabolism KW - Adolescent KW - Astrocytoma KW - drug therapy KW - Cell Line, Tumor KW - Cell Proliferation KW - drug effects KW - Cell Survival KW - Chemotherapy, Adjuvant KW - Child KW - Child, Preschool KW - Drug Resistance, Neoplasm KW - Female KW - Gene Expression Regulation, Neoplastic KW - Humans KW - Infant KW - Male KW - NF-kappa B KW - genetics KW - Neoadjuvant Therapy KW - Neoplasm Recurrence, Local KW - Phosphatidylinositol 3-Kinases KW - Proto-Oncogene Proteins c-akt KW - Signal Transduction KW - Up-Regulation N1 - Publication Type: Journal Article UR - https://doi.org/10.1186/s12943-017-0593-z ER -