He, Yupeng

The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex. [electronic resource] - Nature chemical biology 04 2017 - 389-395 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't

1552-4469

10.1038/nchembio.2306 doi


Antineoplastic Agents--chemistry
Cell Line, Tumor
Cell Proliferation--drug effects
Cell Survival--drug effects
Dose-Response Relationship, Drug
Drug Screening Assays, Antitumor
Humans
Indans--chemistry
Models, Molecular
Molecular Structure
Polycomb Repressive Complex 2--antagonists & inhibitors
Protein Binding--drug effects
Structure-Activity Relationship
Sulfonamides--chemistry
Tumor Cells, Cultured