TY - GEN AU - Tsoi,Ho AU - Chu,Eagle S H AU - Zhang,Xiang AU - Sheng,Jianqiu AU - Nakatsu,Geicho AU - Ng,Siew C AU - Chan,Anthony W H AU - Chan,Francis K L AU - Sung,Joseph J Y AU - Yu,Jun TI - Peptostreptococcus anaerobius Induces Intracellular Cholesterol Biosynthesis in Colon Cells to Induce Proliferation and Causes Dysplasia in Mice SN - 1528-0012 PY - 2017///0808 KW - AMP-Activated Protein Kinases KW - genetics KW - Acetophenones KW - pharmacology KW - Adenoma KW - metabolism KW - Aged KW - Animals KW - Azoxymethane KW - Biopsy KW - Biosynthetic Pathways KW - Caco-2 Cells KW - Case-Control Studies KW - Cell Proliferation KW - Cholesterol KW - biosynthesis KW - Colon KW - microbiology KW - Colonic Neoplasms KW - chemically induced KW - DNA, Bacterial KW - analysis KW - Enzyme Inhibitors KW - Feces KW - Gene Expression KW - Gram-Positive Bacterial Infections KW - complications KW - HT29 Cells KW - Humans KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Middle Aged KW - Peptostreptococcus KW - isolation & purification KW - Reactive Oxygen Species KW - Signal Transduction KW - Sterol Regulatory Element Binding Protein 2 KW - Toll-Like Receptor 2 KW - Toll-Like Receptor 4 KW - Up-Regulation N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1053/j.gastro.2017.01.009 ER -