Tsoi, Ho

Peptostreptococcus anaerobius Induces Intracellular Cholesterol Biosynthesis in Colon Cells to Induce Proliferation and Causes Dysplasia in Mice. [electronic resource] - Gastroenterology 05 2017 - 1419-1433.e5 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1528-0012

10.1053/j.gastro.2017.01.009 doi


AMP-Activated Protein Kinases--genetics
Acetophenones--pharmacology
Adenoma--metabolism
Aged
Animals
Azoxymethane
Biopsy
Biosynthetic Pathways--genetics
Caco-2 Cells
Case-Control Studies
Cell Proliferation
Cholesterol--biosynthesis
Colon--microbiology
Colonic Neoplasms--chemically induced
DNA, Bacterial--analysis
Enzyme Inhibitors--pharmacology
Feces--microbiology
Gene Expression
Gram-Positive Bacterial Infections--complications
HT29 Cells
Humans
Male
Mice
Mice, Inbred C57BL
Middle Aged
Peptostreptococcus--isolation & purification
Reactive Oxygen Species--metabolism
Signal Transduction--genetics
Sterol Regulatory Element Binding Protein 2--metabolism
Toll-Like Receptor 2--genetics
Toll-Like Receptor 4--genetics
Up-Regulation