TY - GEN AU - Netzer,William J AU - Bettayeb,Karima AU - Sinha,Subhash C AU - Flajolet,Marc AU - Greengard,Paul AU - Bustos,Victor TI - Gleevec shifts APP processing from a β-cleavage to a nonamyloidogenic cleavage SN - 1091-6490 PY - 2018///0416 KW - Alzheimer Disease KW - genetics KW - Amyloid Precursor Protein Secretases KW - antagonists & inhibitors KW - Amyloid beta-Peptides KW - metabolism KW - Amyloid beta-Protein Precursor KW - Animals KW - Aspartic Acid Endopeptidases KW - Brain KW - drug effects KW - Cell Line, Tumor KW - Humans KW - Imatinib Mesylate KW - pharmacology KW - Mice, Inbred C57BL KW - Mice, Transgenic KW - Peptide Fragments KW - Protein Kinase Inhibitors KW - Proteolysis N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1073/pnas.1620963114 ER -