Yang, Xiao-Fei
In vivo direct reprogramming of liver cells to insulin producing cells by virus-free overexpression of defined factors. [electronic resource]
- Endocrine journal Mar 2017
- 291-302 p. digital
Publication Type: Journal Article
ISSN: 1348-4540
Standard No.: 10.1507/endocrj.EJ16-0463 doi
Subjects--Topical Terms: Animals Basic Helix-Loop-Helix Transcription Factors--genetics Biomarkers--blood Blood Glucose--analysis Cell Transdifferentiation Diabetes Mellitus, Experimental--blood Gene Transfer Techniques--adverse effects Hepatocytes--metabolism Homeodomain Proteins--genetics Hydrodynamics Injections, Intravenous Insulin--blood Insulin Secretion Insulin-Secreting Cells--metabolism Maf Transcription Factors, Large--genetics Male Mice, Inbred C57BL Nerve Tissue Proteins--genetics Plasmids--administration & dosage RNA, Messenger--metabolism Specific Pathogen-Free Organisms Tail Trans-Activators--genetics Up-Regulation Urocortins--genetics