TY  - GEN
AU  - Dey,Prasenjit
AU  - Baddour,Joelle
AU  - Muller,Florian
AU  - Wu,Chia Chin
AU  - Wang,Huamin
AU  - Liao,Wen-Ting
AU  - Lan,Zangdao
AU  - Chen,Alina
AU  - Gutschner,Tony
AU  - Kang,Yaan
AU  - Fleming,Jason
AU  - Satani,Nikunj
AU  - Zhao,Di
AU  - Achreja,Abhinav
AU  - Yang,Lifeng
AU  - Lee,Jiyoon
AU  - Chang,Edward
AU  - Genovese,Giannicola
AU  - Viale,Andrea
AU  - Ying,Haoqiang
AU  - Draetta,Giulio
AU  - Maitra,Anirban
AU  - Wang,Y Alan
AU  - Nagrath,Deepak
AU  - DePinho,Ronald A
TI  - Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer
SN  - 1476-4687
PY  - 2017///0616
KW  - AMP-Activated Protein Kinases
KW  - metabolism
KW  - Amino Acids, Branched-Chain
KW  - Animals
KW  - Biocatalysis
KW  - Carcinoma, Pancreatic Ductal
KW  - enzymology
KW  - Gene Deletion
KW  - Humans
KW  - Ketoglutaric Acids
KW  - Malate Dehydrogenase
KW  - deficiency
KW  - Male
KW  - Mice
KW  - Minor Histocompatibility Antigens
KW  - biosynthesis
KW  - Mitochondria
KW  - NADP
KW  - Pancreatic Neoplasms
KW  - Pregnancy Proteins
KW  - Reactive Oxygen Species
KW  - Sterol Regulatory Element Binding Protein 1
KW  - Transaminases
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1038/nature21052
ER  -