Plock, N <br/><br/>
Pharmacokinetic/Pharmacodynamic Modeling of the PDE4 Inhibitor TAK-648 in Type 2 Diabetes: Early Translational Approaches for Human Dose Prediction.  [electronic resource] 

 -  Clinical and translational science  05 2017 
 - 185-193 p.  digital 
<br/><br/> Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial 
<br/><br/><label>ISSN: </label>1752-8062 
<br/><br/><label>Standard No.: </label>10.1111/cts.12436  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adult<br/>Aminopyridines--adverse effects<br/>Animals<br/>Area Under Curve<br/>Benzamides--adverse effects<br/>Cyclopropanes--adverse effects<br/>Diabetes Mellitus, Type 2--blood<br/>Dose-Response Relationship, Drug<br/>Female<br/>Humans<br/>Male<br/>Mice<br/>Middle Aged<br/>Models, Biological<br/>Phosphodiesterase 4 Inhibitors--adverse effects<br/>Translational Research, Biomedical