TY - GEN AU - Kasanmoentalib,E Soemirien AU - Valls Seron,Mercedes AU - Ferwerda,Bart AU - Tanck,Michael W AU - Zwinderman,Aeilko H AU - Baas,Frank AU - van der Ende,Arie AU - Schwaeble,William J AU - Brouwer,Matthijs C AU - van de Beek,Diederik TI - Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis SN - 1742-2094 PY - 2017///1011 KW - Aged KW - Animals KW - Anti-Bacterial Agents KW - pharmacology KW - Antibodies KW - adverse effects KW - Ceftriaxone KW - Cohort Studies KW - Cytokines KW - genetics KW - Disease Models, Animal KW - Female KW - Freund's Adjuvant KW - Gene Expression Regulation KW - drug effects KW - Glasgow Outcome Scale KW - Humans KW - Male KW - Mannose-Binding Protein-Associated Serine Proteases KW - cerebrospinal fluid KW - Meningitis, Pneumococcal KW - Mice KW - Mice, Inbred C57BL KW - Mice, Transgenic KW - Middle Aged KW - Time Factors N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1186/s12974-016-0770-9 ER -