TY - GEN AU - Palshof,Jesper Andreas AU - Høgdall,Estrid Vilma Solyom AU - Poulsen,Tim Svenstrup AU - Linnemann,Dorte AU - Jensen,Benny Vittrup AU - Pfeiffer,Per AU - Tarpgaard,Line Schmidt AU - Brünner,Nils AU - Stenvang,Jan AU - Yilmaz,Mette AU - Nielsen,Dorte Lisbet TI - Topoisomerase I copy number alterations as biomarker for irinotecan efficacy in metastatic colorectal cancer SN - 1471-2407 PY - 2018///0227 KW - Aged KW - Antineoplastic Agents, Phytogenic KW - therapeutic use KW - Biomarkers, Tumor KW - Camptothecin KW - analogs & derivatives KW - Colorectal Neoplasms KW - drug therapy KW - DNA Topoisomerases, Type I KW - genetics KW - Disease-Free Survival KW - Female KW - Gene Dosage KW - Humans KW - Irinotecan KW - Liver Neoplasms KW - secondary KW - Lung Neoplasms KW - Male KW - Middle Aged KW - Treatment Outcome N1 - Publication Type: Journal Article UR - https://doi.org/10.1186/s12885-016-3001-y ER -