TY - GEN AU - Herold,Nikolas AU - Rudd,Sean G AU - Ljungblad,Linda AU - Sanjiv,Kumar AU - Myrberg,Ida Hed AU - Paulin,Cynthia B J AU - Heshmati,Yaser AU - Hagenkort,Anna AU - Kutzner,Juliane AU - Page,Brent D G AU - Calderón-Montaño,José M AU - Loseva,Olga AU - Jemth,Ann-Sofie AU - Bulli,Lorenzo AU - Axelsson,Hanna AU - Tesi,Bianca AU - Valerie,Nicholas C K AU - Höglund,Andreas AU - Bladh,Julia AU - Wiita,Elisée AU - Sundin,Mikael AU - Uhlin,Michael AU - Rassidakis,Georgios AU - Heyman,Mats AU - Tamm,Katja Pokrovskaja AU - Warpman-Berglund,Ulrika AU - Walfridsson,Julian AU - Lehmann,Sören AU - Grandér,Dan AU - Lundbäck,Thomas AU - Kogner,Per AU - Henter,Jan-Inge AU - Helleday,Thomas AU - Schaller,Torsten TI - Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies SN - 1546-170X PY - 2017///0814 KW - Adolescent KW - Adult KW - Aged KW - Aged, 80 and over KW - Animals KW - Antimetabolites, Antineoplastic KW - pharmacology KW - Antineoplastic Combined Chemotherapy Protocols KW - Apoptosis KW - drug effects KW - Arabinofuranosylcytosine Triphosphate KW - metabolism KW - Child KW - Child, Preschool KW - Cytarabine KW - Disease Models, Animal KW - Female KW - Humans KW - In Vitro Techniques KW - Infant KW - Leukemia, Myeloid, Acute KW - drug therapy KW - Male KW - Mice KW - Molecular Targeted Therapy KW - Monomeric GTP-Binding Proteins KW - Prognosis KW - SAM Domain and HD Domain-Containing Protein 1 KW - Viral Regulatory and Accessory Proteins N1 - Publication Type: Journal Article; Video-Audio Media UR - https://doi.org/10.1038/nm.4265 ER -