Determination of a natural DNMT1 inhibitor, peperomin E, in rat plasma by UFLC-MS/MS and method application in a pharmacokinetic study. [electronic resource]
- Biomedical chromatography : BMC Aug 2017
Publication Type: Journal Article; Validation Study
1099-0801
10.1002/bmc.3930 doi
Administration, Oral Animals Benzodioxoles--administration & dosage Chromatography, High Pressure Liquid--methods DNA (Cytosine-5-)-Methyltransferase 1 DNA (Cytosine-5-)-Methyltransferases--antagonists & inhibitors Enzyme Inhibitors--administration & dosage Limit of Detection Male Peperomia--chemistry Rats Rats, Sprague-Dawley Tandem Mass Spectrometry--methods