TY - GEN AU - Mu,Ping AU - Zhang,Zeda AU - Benelli,Matteo AU - Karthaus,Wouter R AU - Hoover,Elizabeth AU - Chen,Chi-Chao AU - Wongvipat,John AU - Ku,Sheng-Yu AU - Gao,Dong AU - Cao,Zhen AU - Shah,Neel AU - Adams,Elizabeth J AU - Abida,Wassim AU - Watson,Philip A AU - Prandi,Davide AU - Huang,Chun-Hao AU - de Stanchina,Elisa AU - Lowe,Scott W AU - Ellis,Leigh AU - Beltran,Himisha AU - Rubin,Mark A AU - Goodrich,David W AU - Demichelis,Francesca AU - Sawyers,Charles L TI - SOX2 promotes lineage plasticity and antiandrogen resistance in TP53- and RB1-deficient prostate cancer SN - 1095-9203 PY - 2017///0802 KW - Androgen Antagonists KW - therapeutic use KW - Benzamides KW - Cell Line, Tumor KW - Cell Lineage KW - Cell Plasticity KW - Humans KW - Male KW - Nitriles KW - Phenylthiohydantoin KW - analogs & derivatives KW - Prostatic Neoplasms KW - drug therapy KW - Retinoblastoma Binding Proteins KW - genetics KW - SOXB1 Transcription Factors KW - Tumor Suppressor Protein p53 KW - Ubiquitin-Protein Ligases N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1126/science.aah4307 ER -