Alsayed, Shahinda S R

Design, synthesis and biological screening of some novel celecoxib and etoricoxib analogs with promising COX-2 selectivity, anti-inflammatory activity and gastric safety profile. [electronic resource] - Bioorganic chemistry 02 2017 - 173-183 p. digital

Publication Type: Journal Article

1090-2120

10.1016/j.bioorg.2016.12.008 doi


Animals
Anti-Inflammatory Agents--adverse effects
Celecoxib--adverse effects
Cyclooxygenase 2--metabolism
Cyclooxygenase 2 Inhibitors--adverse effects
Edema--drug therapy
Etoricoxib
Female
Mice
Pyrazoles--adverse effects
Pyridines--adverse effects
Rats
Stomach Ulcer--chemically induced
Sulfones--adverse effects