TY - GEN AU - Isono,Makoto AU - Hoffmann,Michèle J AU - Pinkerneil,Maria AU - Sato,Akinori AU - Michaelis,Martin AU - Cinatl,Jindrich AU - Niegisch,Günter AU - Schulz,Wolfgang A TI - Checkpoint kinase inhibitor AZD7762 strongly sensitises urothelial carcinoma cells to gemcitabine SN - 1756-9966 PY - 2017///1213 KW - Antimetabolites, Antineoplastic KW - pharmacology KW - Carcinoma, Transitional Cell KW - drug therapy KW - Caspases KW - metabolism KW - Cell Cycle KW - drug effects KW - Cell Line, Tumor KW - Cell Survival KW - Checkpoint Kinase 1 KW - genetics KW - Checkpoint Kinase 2 KW - DNA Damage KW - Deoxycytidine KW - analogs & derivatives KW - Drug Screening Assays, Antitumor KW - Drug Synergism KW - Gene Expression Regulation, Neoplastic KW - Humans KW - Poly(ADP-ribose) Polymerases KW - Protein Kinase Inhibitors KW - RNA, Small Interfering KW - Thiophenes KW - Urea KW - Urinary Bladder Neoplasms KW - Gemcitabine N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1186/s13046-016-0473-1 ER -