TY - GEN AU - Guan,Xiangnan AU - LaPak,Kyle M AU - Hennessey,Rebecca C AU - Yu,Christina Y AU - Shakya,Reena AU - Zhang,Jianying AU - Burd,Christin E TI - Stromal Senescence By Prolonged CDK4/6 Inhibition Potentiates Tumor Growth SN - 1557-3125 PY - 2017///1020 KW - Animals KW - Antineoplastic Agents KW - pharmacology KW - Cell Line, Tumor KW - Cellular Senescence KW - drug effects KW - Cyclin-Dependent Kinase 4 KW - antagonists & inhibitors KW - Cyclin-Dependent Kinase 6 KW - Humans KW - Melanoma, Experimental KW - drug therapy KW - Mice KW - Mice, Inbred C57BL KW - Piperazines KW - Protein Kinase Inhibitors KW - Pyridines KW - Signal Transduction KW - Stromal Cells KW - Tumor Microenvironment N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/1541-7786.MCR-16-0319 ER -