De Rosa, Maria

Design, synthesis and in vitro biological evaluation of oligopeptides targeting E. coli type I signal peptidase (LepB). [electronic resource] - Bioorganic & medicinal chemistry 02 2017 - 897-911 p. digital

Publication Type: Journal Article

1464-3391

10.1016/j.bmc.2016.12.003 doi


Cell Survival--drug effects
Dose-Response Relationship, Drug
Drug Design
Escherichia coli--enzymology
Hep G2 Cells
Humans
Membrane Proteins--antagonists & inhibitors
Models, Molecular
Molecular Structure
Oligopeptides--chemical synthesis
Serine Endopeptidases--metabolism
Structure-Activity Relationship