Zhen, Mao-Chuan <br/><br/>
Identification of mTOR as a primary resistance factor of the IAP antagonist AT406 in hepatocellular carcinoma cells.  [electronic resource] 

 -  Oncotarget  Feb 2017 
 - 9466-9475 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1949-2553 
<br/><br/><label>Standard No.: </label>10.18632/oncotarget.14326  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acetates--pharmacology<br/>Animals<br/>Antineoplastic Agents--pharmacology<br/>Antineoplastic Combined Chemotherapy Protocols--pharmacology<br/>Apoptosis--drug effects<br/>Azocines--pharmacology<br/>Benzhydryl Compounds--pharmacology<br/>Benzopyrans--pharmacology<br/>Carcinoma, Hepatocellular--drug therapy<br/>Dose-Response Relationship, Drug<br/>Drug Resistance, Neoplasm--drug effects<br/>Female<br/>Hep G2 Cells<br/>Humans<br/>Imidazoles--pharmacology<br/>Inhibitor of Apoptosis Proteins--antagonists & inhibitors<br/>Liver Neoplasms--drug therapy<br/>Mice, Nude<br/>Mutation<br/>Myeloid Cell Leukemia Sequence 1 Protein--genetics<br/>Protein Kinase Inhibitors--pharmacology<br/>Protein Stability<br/>Proteolysis<br/>RNA Interference<br/>Ribosomal Protein S6 Kinases, 70-kDa--genetics<br/>Signal Transduction--drug effects<br/>TOR Serine-Threonine Kinases--antagonists & inhibitors<br/>Time Factors<br/>Transfection<br/>Triazines--pharmacology<br/>Tumor Burden--drug effects<br/>Ubiquitin-Protein Ligases--antagonists & inhibitors<br/>X-Linked Inhibitor of Apoptosis Protein--antagonists & inhibitors<br/>Xenograft Model Antitumor Assays