TY  - GEN
AU  - Song,Doona
AU  - Lee,Chulho
AU  - Kook,Yoon Jeong
AU  - Oh,Soo Jin
AU  - Kang,Jong Soon
AU  - Kim,Hyun-Jung
AU  - Han,Gyoonhee
TI  - Improving potency and metabolic stability by introducing an alkenyl linker to pyridine-based histone deacetylase inhibitors for orally available RUNX3 modulators
SN  - 1768-3254
PY  - 2017///0222
KW  - Acetylation
KW  - Administration, Oral
KW  - Animals
KW  - Biological Availability
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - drug effects
KW  - Core Binding Factor Alpha 3 Subunit
KW  - chemistry
KW  - Drug Stability
KW  - Female
KW  - Histone Deacetylase Inhibitors
KW  - Histone Deacetylases
KW  - metabolism
KW  - Humans
KW  - Mice
KW  - Microsomes
KW  - Protein Stability
KW  - Pyridines
KW  - Structure-Activity Relationship
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.ejmech.2016.11.055
ER  -