TY - GEN AU - Mathios,Dimitrios AU - Kim,Jennifer E AU - Mangraviti,Antonella AU - Phallen,Jillian AU - Park,Chul-Kee AU - Jackson,Christopher M AU - Garzon-Muvdi,Tomas AU - Kim,Eileen AU - Theodros,Debebe AU - Polanczyk,Magdalena AU - Martin,Allison M AU - Suk,Ian AU - Ye,Xiaobu AU - Tyler,Betty AU - Bettegowda,Chetan AU - Brem,Henry AU - Pardoll,Drew M AU - Lim,Michael TI - Anti-PD-1 antitumor immunity is enhanced by local and abrogated by systemic chemotherapy in GBM SN - 1946-6242 PY - 2017///1229 KW - Animals KW - Antibodies, Monoclonal KW - pharmacology KW - Antibodies, Neoplasm KW - Antineoplastic Agents KW - Brain Neoplasms KW - drug therapy KW - Carmustine KW - Cell Line, Tumor KW - Disease Models, Animal KW - Disease Progression KW - Female KW - Flow Cytometry KW - Glioblastoma KW - Glioma KW - Humans KW - Immunosuppressive Agents KW - Immunotherapy KW - Mice KW - Mice, Inbred C57BL KW - Microglia KW - metabolism KW - Programmed Cell Death 1 Receptor KW - immunology KW - Treatment Outcome N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1126/scitranslmed.aag2942 ER -