TY - GEN AU - Schneider,Constanze AU - Oellerich,Thomas AU - Baldauf,Hanna-Mari AU - Schwarz,Sarah-Marie AU - Thomas,Dominique AU - Flick,Robert AU - Bohnenberger,Hanibal AU - Kaderali,Lars AU - Stegmann,Lena AU - Cremer,Anjali AU - Martin,Margarethe AU - Lohmeyer,Julian AU - Michaelis,Martin AU - Hornung,Veit AU - Schliemann,Christoph AU - Berdel,Wolfgang E AU - Hartmann,Wolfgang AU - Wardelmann,Eva AU - Comoglio,Federico AU - Hansmann,Martin-Leo AU - Yakunin,Alexander F AU - Geisslinger,Gerd AU - Ströbel,Philipp AU - Ferreirós,Nerea AU - Serve,Hubert AU - Keppler,Oliver T AU - Cinatl,Jindrich TI - SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia SN - 1546-170X PY - 2017///0814 KW - Adolescent KW - Adult KW - Aged KW - Aged, 80 and over KW - Animals KW - Antimetabolites, Antineoplastic KW - pharmacology KW - Antineoplastic Combined Chemotherapy Protocols KW - therapeutic use KW - Apoptosis KW - drug effects KW - Cell Line, Tumor KW - Cytarabine KW - administration & dosage KW - Daunorubicin KW - Disease Models, Animal KW - Female KW - Flow Cytometry KW - Humans KW - Immunoblotting KW - Leukemia, Myeloid, Acute KW - drug therapy KW - Male KW - Middle Aged KW - Monomeric GTP-Binding Proteins KW - metabolism KW - Prognosis KW - Retrospective Studies KW - SAM Domain and HD Domain-Containing Protein 1 KW - Young Adult N1 - Publication Type: Journal Article UR - https://doi.org/10.1038/nm.4255 ER -