TY - GEN AU - Raghu,Harini AU - Lepus,Christin M AU - Wang,Qian AU - Wong,Heidi H AU - Lingampalli,Nithya AU - Oliviero,Francesca AU - Punzi,Leonardo AU - Giori,Nicholas J AU - Goodman,Stuart B AU - Chu,Constance R AU - Sokolove,Jeremy B AU - Robinson,William H TI - CCL2/CCR2, but not CCL5/CCR5, mediates monocyte recruitment, inflammation and cartilage destruction in osteoarthritis SN - 1468-2060 PY - 2017///0613 KW - Animals KW - Cartilage, Articular KW - pathology KW - Chemokine CCL2 KW - genetics KW - Chemokine CCL5 KW - Chemokines KW - Chemotaxis KW - Fibroblasts KW - metabolism KW - Gene Expression KW - Humans KW - Indazoles KW - pharmacology KW - Leukocyte Count KW - Macrophages KW - Male KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Monocytes KW - physiology KW - Osteoarthritis KW - Propionates KW - RNA, Messenger KW - Receptors, CCR2 KW - antagonists & inhibitors KW - Receptors, CCR5 KW - Signal Transduction KW - drug effects KW - Synovial Fluid N1 - Publication Type: Journal Article UR - https://doi.org/10.1136/annrheumdis-2016-210426 ER -