PEG-functionalized zinc oxide nanoparticles induce apoptosis in breast cancer cells through reactive oxygen species-dependent impairment of DNA damage repair enzyme NEIL2. [electronic resource]
- Free radical biology & medicine 02 2017
- 35-47 p. digital
Publication Type: Journal Article
1873-4596
10.1016/j.freeradbiomed.2016.11.048 doi
Antineoplastic Agents--chemical synthesis Apoptosis--drug effects Breast Neoplasms DNA Glycosylases--metabolism DNA-(Apurinic or Apyrimidinic Site) Lyase--metabolism Drug Screening Assays, Antitumor Female Humans MCF-7 Cells Metal Nanoparticles--chemistry Oxidative Stress--drug effects Particle Size Polyethylene Glycols--chemical synthesis Reactive Oxygen Species--metabolism Zinc Oxide--chemical synthesis