TY  - GEN
AU  - Li,Ming
AU  - de Graaf,Inge A M
AU  - van de Steeg,Evita
AU  - de Jager,Marina H
AU  - Groothuis,Geny M M
TI  - The consequence of regional gradients of P-gp and CYP3A4 for drug-drug interactions by P-gp inhibitors and the P-gp/CYP3A4 interplay in the human intestine ex vivo
SN  - 1879-3177
PY  - 2017///0726
KW  - ATP Binding Cassette Transporter, Subfamily B, Member 1
KW  - antagonists & inhibitors
KW  - Adult
KW  - Aged
KW  - Aged, 80 and over
KW  - Colon
KW  - metabolism
KW  - Cyclosporins
KW  - pharmacology
KW  - Cytochrome P-450 CYP3A
KW  - Cytochrome P-450 CYP3A Inhibitors
KW  - Drug Interactions
KW  - Female
KW  - Humans
KW  - Ileum
KW  - In Vitro Techniques
KW  - Isoquinolines
KW  - Jejunum
KW  - Ketoconazole
KW  - Male
KW  - Middle Aged
KW  - Quinazolines
KW  - Quinidine
KW  - analogs & derivatives
KW  - Verapamil
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.tiv.2016.12.002
ER  -